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We are interested in advancing biomedical science by developing technologies that redefine the boundaries of discovery. We develop next-generation antibodies with unmatched precision to diagnose and treat infectious diseases, cancer, and autoimmune disorders. Leveraging cutting-edge tools in protein engineering and design, artificial intelligence, and proteomics, we aim to uncover novel biology and accelerate the drug discovery process. Through interdisciplinary collaboration, we bridge the gap between basic science and translational medicine, delivering innovative solutions to some of the most pressing challenges in human health. Our lab is dedicated to fostering a collaborative and inclusive environment where curiosity, creativity, and scientific rigor drive groundbreaking advancements.

Research Statement

10/23/2024: Our AMETA technology is now published at Cell. Congratulations Yufei, Zhe and Pham! What an incredible journey!!!🎉

10/01/2024: Congratulations, Paul, on receiving the NIH T32 Postdoctoral Fellowship! 🎉

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Huge thank you to our supports!

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© 2022 by Shi Lab Icahn School of Medicine at Mount Sinai, NY

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